![]() When entering a gate of a magnificent city we can make a prediction about the splendor, pomposity, history, and civilization we will encounter in the city. In this review, we aim to convey the principles of writing the introduction section of a manuscript to residents and young investigators who have just begun to write a manuscript. To do this, the subject of the article should be thoroughly reviewed, and the aim of the study should be clearly stated immediately after discussing the basic references. The main goal of the introduction is to convey basic information to the readers without obligating them to investigate previous publications and to provide clues as to the results of the present study. Additionally, abbreviations and explanations are included in this section. ![]() The introduction section comprises the first portion of the manuscript, and it should be written using the simple present tense. Writing should begin when the experimental system and the equipment are available. Before writing the introduction, the main steps, the heading and the familiarity level of the readers should be considered. An article primarily includes the following sections: introduction, materials and methods, results, discussion, and conclusion.
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